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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2171429Generated: November 1, 2026

(3,5-Difluoro-4-(3-fluorophenoxy)phenyl)methanol → (S)-7-((3,5-difluoro-4-(3-fluorophenoxy)benzyl)oxy)-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one

https://huagongshe.com/reaction/2171429

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3,5-Difluoro-4-(3-fluorophenoxy)phenyl)methanolHCID 63077760—
Reactant(S)-7-chloro-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 86728322—
Product(S)-7-((3,5-difluoro-4-(3-fluorophenoxy)benzyl)oxy)-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 86728412—

Reaction Steps

The title compound was prepared by a procedure similar to that described for E9 starting from (3,5-difluoro-4-(3-fluorophenoxy)phenyl)methanol and (S)-7-chloro-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09051325B2
Source datasetuspto-grants-2015_06
ORD IDord-cd1e4045bdbe4b21a202b1d9afb0fe1b
Source noteuspto-grants-2015_06