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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2171440Generated: November 1, 2026

2,5-Difluorobenzyl alcohol → 7-((2,5-difluorobenzyl)oxy)-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one

https://huagongshe.com/reaction/2171440

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,5-Difluorobenzyl alcoholHCID 522599—
Reactant7-chloro-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 86728345—
Product7-((2,5-difluorobenzyl)oxy)-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 86728423—

Reaction Steps

The title compound was prepared by a procedure similar to that described for E9 starting from (2,5-difluorophenyl)methanol and 7-chloro-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09051325B2
Source datasetuspto-grants-2015_06
ORD IDord-91abe5b1503847f5bec494f6d4729f68
Source noteuspto-grants-2015_06