3,4,5-Trifluorobenzyl alcohol → HCID 86728436, compound

HRID 2171451Notes

Reaction equation

HRID 2171451 reaction equation
Cl[C:2]1[CH:3]=[C:4]2[N:11]([CH3:12])[C:10]([CH3:14])([CH3:13])[CH2:9][N:5]2[C:6](=[O:8])[N:7]=1.[F:15][C:16]1[CH:17]=[C:18]([CH2:24][OH:25])[CH:19]=[C:20]([F:23])[C:21]=1[F:22]>>[CH3:12][N:11]1[C:4]2[N:5]([C:6](=[O:8])[N:7]=[C:2]([O:25][CH2:24][C:18]3[CH:19]=[C:20]([F:23])[C:21]([F:22])=[C:16]([F:15])[CH:17]=3)[CH:3]=2)[CH2:9][C:10]1([CH3:14])[CH3:13]

Participants

3

Reactant 2

HCID 27770403,4,5-Trifluorobenzyl alcoholHCID 867283457-chloro-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one

Product 1

HCID 86728436HCID 86728436, compound

Procedure

The title compound was prepared by a procedure similar to that described for E1 starting from 7-chloro-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one and (3,4,5-trifluorophenyl)methanol.

Sources & evidence

ORD record
ord-d029c17e1ce9410eaedeae51e4cfa3de
Source dataset
uspto-grants-2015_06
Patent number
US09051325B2

Reaction notes

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