2-(3,4-Difluorophenyl)ethan-1-ol → HCID 86728444, compound

HRID 2171458Notes

Reaction equation

HRID 2171458 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH2:9][CH2:10][OH:11])[CH:5]=[CH:6][C:7]=1[F:8].Cl[C:13]1[CH:14]=[C:15]2[N:22]([CH3:23])[C:21]([CH3:25])([CH3:24])[CH2:20][N:16]2[C:17](=[O:19])[N:18]=1>>[F:1][C:2]1[CH:3]=[C:4]([CH:5]=[CH:6][C:7]=1[F:8])[CH2:9][CH2:10][O:11][C:13]1[CH:14]=[C:15]2[N:22]([CH3:23])[C:21]([CH3:25])([CH3:24])[CH2:20][N:16]2[C:17](=[O:19])[N:18]=1

Participants

3

Reactant 2

HCID 27583132-(3,4-Difluorophenyl)ethan-1-olHCID 867283457-chloro-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one

Product 1

HCID 86728444HCID 86728444, compound

Procedure

The title compound was prepared by a procedure similar to that described for E9 starting from 2-(3,4-difluorophenyl)ethanol and 7-chloro-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one.

Sources & evidence

ORD record
ord-441f05384cbc47c8823223200643a781
Source dataset
uspto-grants-2015_06
Patent number
US09051325B2

Reaction notes

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