HCID 71240253, compound → HCID 86728446, compound

HRID 2171460Notes

Reaction equation

HRID 2171460 reaction equation
Cl[C:2]1[CH:3]=[C:4]2[N:11]([CH3:12])[CH:10]([CH3:13])[CH2:9][N:5]2[C:6](=[O:8])[N:7]=1.[F:14][C:15]1[CH:16]=[C:17]([CH2:33][OH:34])[CH:18]=[CH:19][C:20]=1[O:21][C:22]1[CH:27]=[C:26]([C:28]([F:31])([F:30])[F:29])[CH:25]=[C:24]([F:32])[CH:23]=1>>[F:14][C:15]1[CH:16]=[C:17]([CH:18]=[CH:19][C:20]=1[O:21][C:22]1[CH:27]=[C:26]([C:28]([F:29])([F:30])[F:31])[CH:25]=[C:24]([F:32])[CH:23]=1)[CH2:33][O:34][C:2]1[CH:3]=[C:4]2[N:11]([CH3:12])[CH:10]([CH3:13])[CH2:9][N:5]2[C:6](=[O:8])[N:7]=1

Participants

3

Reactant 2

HCID 71240253HCID 71240253, compoundHCID 867283147-chloro-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one

Product 1

HCID 86728446HCID 86728446, compound

Procedure

The title compound was prepared by a procedure similar to that described for E9 starting from 7-chloro-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one and (3-fluo-ro-4-(3-fluoro-5-(trifluoromethyl)phenoxy)phenyl)methanol.

Sources & evidence

ORD record
ord-ba2409fa52a94cc2b9e9d7db51be7567
Source dataset
uspto-grants-2015_06
Patent number
US09051325B2

Reaction notes

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