3-(Hydroxymethyl)benzonitrile → HCID 86728449, compound

HRID 2171463Notes

Reaction equation

HRID 2171463 reaction equation
[OH:1][CH2:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[C:6]#[N:7].Cl[C:12]1[CH:13]=[C:14]2[N:21]([CH3:22])[C:20]([CH3:24])([CH3:23])[CH2:19][N:15]2[C:16](=[O:18])[N:17]=1>>[CH3:22][N:21]1[C:14]2[N:15]([C:16](=[O:18])[N:17]=[C:12]([O:1][CH2:2][C:3]3[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=3)[C:6]#[N:7])[CH:13]=2)[CH2:19][C:20]1([CH3:24])[CH3:23]

Participants

3

Reactant 2

HCID 27346773-(Hydroxymethyl)benzonitrileHCID 867283457-chloro-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one

Product 1

HCID 86728449HCID 86728449, compound

Procedure

The title compound was prepared by a procedure similar to that described for E9 starting from 3-(hydroxymethyl)benzonitrile and 7-chloro-1,2,2-trimethyl-2,3-dihydroimidazo-[1,2-c]pyrimidin-5(1H)-one.

Sources & evidence

ORD record
ord-89f8c1f14d7b4484bbe40669ce7d7084
Source dataset
uspto-grants-2015_06
Patent number
US09051325B2

Reaction notes

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