HCID 63076546, compound → HCID 86728451, compound

HRID 2171465Notes

Reaction equation

HRID 2171465 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:16]=[CH:17][C:18]=1[F:19])[O:5][C:6]1[C:11]([F:12])=[CH:10][C:9]([CH2:13][OH:14])=[CH:8][C:7]=1[F:15].Cl[C:21]1[CH:22]=[C:23]2[N:30]([CH3:31])[C@@H:29]([CH3:32])[CH2:28][N:24]2[C:25](=[O:27])[N:26]=1>>[F:1][C:2]1[CH:3]=[C:4]([CH:16]=[CH:17][C:18]=1[F:19])[O:5][C:6]1[C:7]([F:15])=[CH:8][C:9]([CH2:13][O:14][C:21]2[CH:22]=[C:23]3[N:30]([CH3:31])[C@@H:29]([CH3:32])[CH2:28][N:24]3[C:25](=[O:27])[N:26]=2)=[CH:10][C:11]=1[F:12]

Participants

3

Reactant 2

HCID 63076546HCID 63076546, compoundHCID 86728322(S)-7-chloro-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one

Product 1

HCID 86728451HCID 86728451, compound

Procedure

The title compound was prepared by a procedure similar to that described for E9 starting from (4-(3,4-difluorophenoxy)-3,5-difluorophenyl)methanol and (S)-7-chloro-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one.

Sources & evidence

ORD record
ord-03e306090b4e4341bec2d8b997fdb975
Source dataset
uspto-grants-2015_06
Patent number
US09051325B2

Reaction notes

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