3,5-Difluorobenzyl alcohol → HCID 86728453, compound

HRID 2171467Notes

Reaction equation

HRID 2171467 reaction equation
Cl[C:2]1[CH:3]=[C:4]2[N:11]([CH2:12][CH3:13])[C:10]([CH3:15])([CH3:14])[CH2:9][N:5]2[C:6](=[O:8])[N:7]=1.[F:16][C:17]1[CH:18]=[C:19]([CH2:24][OH:25])[CH:20]=[C:21]([F:23])[CH:22]=1>>[F:16][C:17]1[CH:18]=[C:19]([CH:20]=[C:21]([F:23])[CH:22]=1)[CH2:24][O:25][C:2]1[CH:3]=[C:4]2[N:11]([CH2:12][CH3:13])[C:10]([CH3:15])([CH3:14])[CH2:9][N:5]2[C:6](=[O:8])[N:7]=1

Participants

3

Reactant 2

HCID 5227213,5-Difluorobenzyl alcoholHCID 86728330HCID 86728330, compound

Product 1

HCID 86728453HCID 86728453, compound

Procedure

The title compound was prepared by a procedure similar to that described for E1 starting from 7-chloro-1-ethyl-2,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one and (3,5-difluorophenyl)methanol.

Sources & evidence

ORD record
ord-f5a431f63ae541d181082021ab1e6249
Source dataset
uspto-grants-2015_06
Patent number
US09051325B2

Reaction notes

Loading…