HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67004364, compound → HCID 67004766, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67004364 | HCID 67004364 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 67004766 | HCID 67004766 | 73.1% |
Reaction Steps
To a solution of 2-nitro-6-pyridin-2-yl-4-pyridin-3-yl-phenylamine (75 mg, 0.26 mmol) in ethyl acetate (20 mL) was added 10% palladium on carbon (50 mg). The resulting suspension was placed in a Parr hydrogenation apparatus under 40 psi hydrogen gas while shaking at ambient temperature for one hour. The catalyst was removed by filtration and the filtrate concentrated in vacuo to afford compound the title compound (50 mg, 0.19 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08193352B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-fe317c13ca5243f7a43a4e126613b7fb |
| Source note | uspto-grants-2012_06 |