2,4-Difluorobenzyl alcohol → HCID 86728456, compound

HRID 2171470Notes

Reaction equation

HRID 2171470 reaction equation
Cl[C:2]1[CH:3]=[C:4]2[N:11]([CH:12]([CH3:14])[CH3:13])[C:10]([CH3:16])([CH3:15])[CH2:9][N:5]2[C:6](=[O:8])[N:7]=1.[F:17][C:18]1[CH:23]=[C:22]([F:24])[CH:21]=[CH:20][C:19]=1[CH2:25][OH:26]>>[F:17][C:18]1[CH:23]=[C:22]([F:24])[CH:21]=[CH:20][C:19]=1[CH2:25][O:26][C:2]1[CH:3]=[C:4]2[N:11]([CH:12]([CH3:14])[CH3:13])[C:10]([CH3:16])([CH3:15])[CH2:9][N:5]2[C:6](=[O:8])[N:7]=1

Participants

3

Reactant 2

HCID 918672,4-Difluorobenzyl alcoholHCID 86728333HCID 86728333, compound

Product 1

HCID 86728456HCID 86728456, compound

Procedure

The title compound was prepared by a procedure similar to that described for E1 starting from 7-chloro-1-isopropyl-2,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one and (2,4-difluorophenyl)methanol.

Sources & evidence

ORD record
ord-a6793623bf994bb78b918b7b678aace2
Source dataset
uspto-grants-2015_06
Patent number
US09051325B2

Reaction notes

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