2-(2-Aminoethylamino)-5-nitropyridine → N-[7-(2,4-Dichlorophenyl)imidazo[1,2-c]pyrimidin-5-yl]-N'-(5-nitropyridin-2-yl)ethane-1,2-diamine

HRID 2171559Notes

Reaction equation

HRID 2171559 reaction equation
Cl[C:2]1[N:7]2[CH:8]=[CH:9][N:10]=[C:6]2[CH:5]=[C:4]([C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][C:12]=2[Cl:18])[N:3]=1.[N+:19]([C:22]1[CH:23]=[CH:24][C:25]([NH:28][CH2:29][CH2:30][NH2:31])=[N:26][CH:27]=1)([O-:21])=[O:20]>>[Cl:18][C:12]1[CH:13]=[C:14]([Cl:17])[CH:15]=[CH:16][C:11]=1[C:4]1[N:3]=[C:2]([NH:31][CH2:30][CH2:29][NH:28][C:25]2[CH:24]=[CH:23][C:22]([N+:19]([O-:21])=[O:20])=[CH:27][N:26]=2)[N:7]2[CH:8]=[CH:9][N:10]=[C:6]2[CH:5]=1

Participants

3

Reactant 2

HCID 1224252-(2-Aminoethylamino)-5-nitropyridineHCID 59312932HCID 59312932, compound

Product 1

HCID 59313031N-[7-(2,4-Dichlorophenyl)imidazo[1,2-c]pyrimidin-5-yl]-N'-(5-nitropyridin-2-yl)ethane-1,2-diamine

Procedure

In analogy to the procedure for preparing Example 7A, the product is obtained as a solid by reacting 5-chloro-7-(2,4-dichlorophenyl)imidazo[1,2-c]pyrimidine (Example 6A) with N-(5-nitropyridin-2-yl)ethane-1,2-diamine

Workup

  1. customIn analogy to the procedure for preparing Example 7A
  2. customthe product is obtained as a solid

Sources & evidence

ORD record
ord-4f8f15d2282c4f1bb82eb59daf4396c9
Source dataset
uspto-grants-2015_06
Patent number
US09051323B2

Reaction notes

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