HuagongsheHuagongshe Chemistry Print Report · For research reference only
Anisole → 5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Anisole | HCID 7519 | — |
| Reactant | 2,5-Dimethyl-2,5-hexanediol | HCID 8031 | — |
| Reactant | Boron tribromide | HCID 25134 | — |
| Reactant | 6-Methoxy-1,1,4,4-tetramethyl-2,3-dihydronaphthalene | HCID 10331003 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ol | HCID 268786 | — |
| Product | 6-Methoxy-1,1,4,4-tetramethyl-2,3-dihydronaphthalene | HCID 10331003 | — |
Reaction Steps
6-Methoxy-1,1,4,4-tetramethyl-1,2,3,4-tetrahydro-naphthalene was prepared employing the procedures described in U.S. Pat. Appl. Publ. 2005/0148590 A1, employing 2,5-dimethyl-hexane-2,5-diol and anisole as the starting materials. 6-Methoxy-1,1,4,4-tetramethyl-1,2,3,4-tetrahydro-naphthalene was subsequently treated with BBr3 in CH2Cl2 to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09051331B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-c3299d83fb3a44d98ca1a52a48efe378 |
| Source note | uspto-grants-2015_06 |