HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → HCID 178432655, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 3-(Benzyloxy)-2-methylpyridin-4(1H)-one | HCID 2726416 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 178432655 | HCID 178432655 | 88% |
Reaction Steps
The above compound 3 (129 g, 599 mmol) was suspended in acetonitrile (1300 ml), and N-bromosuccinic acid imide (117 g, 659 mmol) was added, followed by stirring at room temperature for 90 minutes. Precipitated crystals were filtered, and washed with acetonitrile and diethyl ether to obtain 3-benzyloxy-5-bromo-2-methyl-pyridine-4-ol 4 (154 g, 88%) as a colorless crystal.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09051337B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-f433443fe8934fe293a27665767466f5 |
| Source note | uspto-grants-2015_06 |