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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 217200Generated: October 31, 2026

HCID 57659516, compound → HCID 136189049, compound

https://huagongshe.com/reaction/217200

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57659516HCID 57659516—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
SolventDichloromethaneHCID 6344—
ProductHCID 136189049HCID 136189049—

Reaction Steps

A solution of 4-[5-(3-benzyloxyfuro[3,2-c]pyridin-2-yl)-[1,2,4]oxadiazol-3-ylmethyl]-piperidine-1-carboxylic acid tert-butyl ester (Example 120, 200 mg, 500 μmol) and Pd (10% on C, 10 mg) in EtOH (10 mL) was stirred under a H2 atmosphere for 2.5 h. The mixture was diluted with CH2Cl2, to solubilise the product, before being filtered through celite. The filtrate was concentrated to furnish the title compound: RT=2.87 min; m/z (ES+)=401.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08193359B2
Source datasetuspto-grants-2012_06
ORD IDord-f1862b3edfe844b3b31135755e1a0dde
Source noteuspto-grants-2012_06