HCID 86709376, compound → HCID 67275859, compound

Participants

Reaction Steps

5′-Benzyloxy-4-(4-trifluoromethoxyphenoxy)-3,4,5,6-tetrahydro-2H-[1,2′]bipyridinyl (0.93 g) and 10% palladium on carbon (93 mg) were added to ethanol (9.3 ml), and the mixture was stirred at room temperature under a hydrogen atmosphere (atmospheric pressure) for 1 hour. The catalyst was removed by filtration, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (hexane:ethyl acetate=10:0→6:4). The result was concentrated to dryness under reduced pressure to afford the title compound as a pale yellow powder (0.55 g).

Provenance & Evidence