Methanol → HCID 11384290, compound

Participants

Reaction Steps

Methanol (1 ml) and a catalytic amount of acetic acid and sodium triacetoxyborohydride (0.14 g) were added to a 1,2-dichloroethane solution (5 ml) of 2-piperazin-1-yl-benzothiazol-6-ol (0.1 g) and 4-trifluoromethoxybenzaldehyde (0.067 ml) and stirred at room temperature overnight. Water was added to the reaction mixture, followed by extraction with dichloromethane. The organic layer was washed with water, dried over sodium sulfate, and then concentrated under reduced pressure to afford the title compound as a colorless amorphous compound (80 mg).

Provenance & Evidence