HCID 70873537, compound → HCID 70873738, compound

Participants

Reaction Steps

6-Benzyloxy-1-[3-(4-trifluoromethoxy-phenoxy)propyl]-1,2,3,4-tetrahydro-quinoline (2.13 g) was dissolved in ethanol (10 ml). 10% palladium on carbon (0.2 g) was added thereto and stirred at room temperature under a hydrogen atmosphere for 4 hours. The mixture was filtered through Celite to remove the catalyst, and then the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (hexane:ethyl acetate=4:1) and concentrated under reduced pressure to afford the title compound (1.45 g).

Provenance & Evidence