Hydrochloric Acid → HCID 70873356, compound

Participants

Reaction Conditions

Reaction Steps

4-(4-Benzyloxybenzylidene)piperidine-1-carboxylic acid tert-butyl ester (3.80 g, 10 mmol), ethanol (40 ml) and 1 N hydrochloric acid (25 ml) were mixed and stirred at 80° C. for 1 hour. Ethanol was distilled off under reduced pressure and neutralized with sodium hydroxide. The organic layer was dried over sodium sulfate and concentrated to afford the title compound as a pale yellow powder (2.32 g, 83%).

Provenance & Evidence