1-Octanol → HCID 69239783, compound

Participants

Reaction Steps

To a mixture of 49.9 g (300 mmol) of tropic acid and 5.00 g of montmorillonite K10 in 200 ml of toluene is added dropwise at 110° C. 104 g (800 mmol) of 1-octanol. The reaction mixture is stirred for 8 hours, and then toluene/water are removed by azeotropical distillation. The catalyst residue is filtered off and the filtrate is evaporated to dryness to afford 60.4 g (72%) of 3-hydroxy-2-phenyl-propionic acid octyl ester.

Provenance & Evidence