Sodium Hydroxide → HCID 69234383, compound

HRID 2172350Notes

Reaction equation

HRID 2172350 reaction equation
[CH3:1][O:2][C:3](=[O:13])[C:4]1[CH:9]=[CH:8][C:7]([CH2:10][C:11]#[N:12])=[CH:6][CH:5]=1.[OH-].[Na+]>[I-].C([N+](CCCC)(CCCC)CCCC)CCC.C1(C)C=CC=CC=1>[CH3:1][O:2][C:3](=[O:13])[C:4]1[CH:9]=[CH:8][C:7]([C:10]([C:11]#[N:12])=[CH:3][C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=2)=[CH:6][CH:5]=1

Participants

5

Reactant 2

HCID 14798Sodium HydroxideHCID 848548Methyl 4-(cyanomethyl)benzoate

Product 1

HCID 69234383HCID 69234383, compound

Reagents, catalysts & solvents 2

HCID 67553Tetrabutylammonium IodideCatalystHCID 1140TolueneSolvent

Procedure

is prepared by treating a toluene solution of 4-cyanomethyl-benzoic acid methyl ester (CAS-Number: 76469-88-0), 4-chlorobenzaldheyde, tetrabutylammonium iodide with an aqueous solution of sodium hydroxide according to the following literature: I. P. Beletskaya, N. S. Gulyukina, M. Ali Ali, A. A. Solov'yanov, O. A. Reutov J. Org. Chem. USSR (Engl. Transl.) 1987, 23, 657-661.

Workup

  1. customis prepared

Sources & evidence

ORD record
ord-27dcef1ec317431e8f0cb76ad165aa74
Source dataset
uspto-grants-2015_06
Patent number
US09051448B2

Reaction notes

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