Water → HCID 86690534, compound

Participants

Reaction Conditions

Reaction Steps

To [7-(2-ethyl-hexyl)-3-(2,4,6-trimethylbenzoyl)-7H-benzo[c]carbazole-10-yl]-o-tolyl-methanone (0.25 g, 0.42 mmol) in pyridine (2 ml) is added hydroxylammonium chloride (59 mg, 0.84 mmol). The mixture is heated at 130° C., and then it is stirred for 6 hours. After the reaction mixture is cooled to room temperature, it is poured into water, and then the crude product is extracted with CH2Cl2 and washed with water and brine. After drying over MgSO4 and concentration, the desired product is obtained as a pale yellow solid (0.23 g, 90%). It is composed of an isomeric mixture, and the structure is confirmed by 1H-NMR spectrum (CDCl3) δ [ppm]: 0.84 (t), 0.92 (t), 1.23-1.40 (m), 2.05-2.07 (m), 2.10 (s), 2.18 (s), 2.20 (s), 2.40 (s), 4.32 (dd), 6.97 (s), 7.19 (dd), 7.34-7.38 (m), 7.42 (dd), 7.51 (dd), 7.62 (dd), 7.84 (d), 7.97 (d), 8.12 (dd), 8.61 (br), 9.06 (br).

Provenance & Evidence