Boron Trichloride → HCID 86685816, compound

Participants

Reaction Conditions

Reaction Steps

Azide 11 (103 mg, 0.28 mmol) was dissolved in CH2Cl2 (5 mL) and cooled to −78° C. before BCl3 (5 mL, 1M in CH2Cl2) was added. After 4 h stirring at −78° C., the reaction was quenched by the addition of MeOH. The temperature was raised to room temperature and the solution was concentrated in vacuo. Trace of BCl3 were removed by coevaporating with MeOH. The resulting crude triol 17 was used as such in the click reaction.

Provenance & Evidence