Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2172819Generated: October 31, 2026

Trifluoroacetic acid → HCID 57956741, compound

https://huagongshe.com/reaction/2172819

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 57956850HCID 57956850—
SolventEthanolHCID 702—
ProductHCID 57956741HCID 57956741—

Reaction Steps

To a solution of 2-((2S,3S)-3-(3-(3-hydroxy-3-propylhexyl)phenyl)-2-methyl-3-(trimethylsilyloxy)propyl)isoindoline-1,3-dione in EtOH is added trifluoroacetic acid. The reaction mixture is stirred at room temperature then concentrated under reduced pressure, re-evaporated with EtOAc then with hexane to give 2-((2S,3S)-3-hydroxy-3-(3-(3-hydroxy-3-propylhexyl)phenyl)-2-methylpropyl)isoindoline-1,3-dione.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09056849B2
Source datasetuspto-grants-2015_06
ORD IDord-aa8b1bebf6b9484fa1139a580d183771
Source noteuspto-grants-2015_06