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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2173130Generated: November 1, 2026

4-methyl-5-(2-piperazin-1-ylethyl)-2-benzofuran-1(3H)-one hydrochloride → HCID 67518344, compound

https://huagongshe.com/reaction/2173130

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-methyl-5-(2-piperazin-1-ylethyl)-2-benzofuran-1(3H)-one hydrochlorideHCID 67517229—
ReactantHCID 86692998HCID 86692998—
ProductHCID 67518344HCID 67518344—

Reaction Steps

4-Ethyl-5-[2-(piperazin-1-yl)ethyl]-2-benzofuran-1(3H)-one was prepared in a similar fashion to that described for the synthesis of 4-methyl-5-(2-piperazin-1-ylethyl)-2-benzofuran-1(3H)-one hydrochloride above starting from tert-butyl-4-[2-(4-ethyl-1-oxo-1,3-dihydro-2-benzofuran-5-yl)ethyl]piperazine-1-carboxylate. LC-MS (IE, m/z): 275 [M+1]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09056859B2
Source datasetuspto-grants-2015_06
ORD IDord-3b3022b658ed46279620968706c03fea
Source noteuspto-grants-2015_06