tert-Butoxy bis(dimethylamino)methane → HCID 87429210, compound

Participants

Reaction Steps

A solution of 9-methyl-6H-benzo[c]chromen-6-one (100 mg, 0.476 mmol) in dry DMF (2378 μl) Was treated with TERT-BUTOXY BIS(DIMETHYLAMINO)METHANE (99 mg, 0.571 mmol) at 80° C. in a sealed tube for one hour. The solution turned a deep red color and was cooled, diluted with 2M HCl and stirred for 20 minutes. The solution was then extracted with DCM, the combind orgainc layers were dried, filtered and concentrated with out heat. Crude (6-oxo-6H-benzo[c]chromen-9-yl)acetaldehyde was used without further purification. LC-MS (IE, m/z): 239 [M+1]+.

Provenance & Evidence