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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2173220Generated: November 1, 2026

3-Bromo-6-fluoro-2-methylbenzonitrile → 6-Fluoro-2-methyl-3-(2-oxoethyl)benzonitrile

https://huagongshe.com/reaction/2173220

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-6-fluoro-2-methylbenzonitrileHCID 66643852—
Reactant2-Chloro-6-fluoro-3-(2-oxoethyl)benzonitrileHCID 86693006—
Product6-Fluoro-2-methyl-3-(2-oxoethyl)benzonitrileHCID 86693041—

Reaction Steps

6-Fluoro-2-methyl-3-(2-oxoethyl)benzonitrile was prepared in two steps starting from 3-bromo-6-fluoro-2-methylbenzonitrile in an analogous fashion to that described for the synthesis of 2-chloro-6-fluoro-3-(2-oxoethyl)benzonitrile (Steps B and C) above.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09056859B2
Source datasetuspto-grants-2015_06
ORD IDord-aa9c41276b6e4326ad3a7f3bc4bf9c08
Source noteuspto-grants-2015_06