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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2173222Generated: October 30, 2026

3-Bromo-6-methoxy-2-methylbenzonitrile → 6-Methoxy-2-methyl-3-(2-oxoethyl)benzonitrile

https://huagongshe.com/reaction/2173222

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-6-methoxy-2-methylbenzonitrileHCID 67516064—
Reactant2-Chloro-6-fluoro-3-(2-oxoethyl)benzonitrileHCID 86693006—
Product6-Methoxy-2-methyl-3-(2-oxoethyl)benzonitrileHCID 77230668—

Reaction Steps

6-methoxy-2-methyl-3-(2-oxoethyl)benzonitrile was prepared in two steps starting from 3-bromo-6-methoxy-2-methylbenzonitrile in an analogous fashion to that described for the synthesis of 2-chloro-6-fluoro-3-(2-oxoethyl)benzonitrile (Steps B and C) above.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09056859B2
Source datasetuspto-grants-2015_06
ORD IDord-6fbf69bcdfad4a028e2ba07fd71d50d6
Source noteuspto-grants-2015_06