HuagongsheHuagongshe Chemistry Print Report · For research reference only
Allyltributylstannane → HCID 67515716, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Allyltributylstannane | HCID 90628 | — |
| Reactant | Lithium Chloride | HCID 433294 | — |
| Reactant | HCID 67515500 | HCID 67515500 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 67515716 | HCID 67515716 | — |
Reaction Steps
A mixture of compound 5-bromo-2-fluoro-4-methoxybenzonitrile (10.0 mmol), allyl-tributyl-stannane (12.0 mmol), LiCl (20.0 mmol) and Pd(PPh3)4 (0.2 g) in anhydrous toluene was refluxed under N2 overnight. Distilled off the solvent under reduce pressure, the residue was purified with silica gel cloumn chromatography to give the product 2-fluoro-4-methoxy-5-(prop-2-en-1-yl)benzonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09056859B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-00822376fab04769a98cce051b83561d |
| Source note | uspto-grants-2015_06 |