5-Oxo-5,6,7,8-tetrahydronaphthalene-1-carbonitrile → 5-Formyl-5,6,7,8-tetrahydronaphthalene-1-carbonitrile

HRID 2173251Notes

Reaction equation

HRID 2173251 reaction equation
O=[C:2]1[CH2:11][CH2:10][CH2:9][C:8]2[C:7]([C:12]#[N:13])=[CH:6][CH:5]=[CH:4][C:3]1=2.[CH:14](C1C2C=CC=C(C#N)C=2CC1)=[O:15]>>[CH:14]([CH:2]1[CH2:11][CH2:10][CH2:9][C:8]2[C:7]([C:12]#[N:13])=[CH:6][CH:5]=[CH:4][C:3]1=2)=[O:15]

Participants

3

Reactant 2

HCID 109318735-Oxo-5,6,7,8-tetrahydronaphthalene-1-carbonitrileHCID 595686981-formyl-2,3-dihydro-1H-indene-4-carbonitrile

Product 1

HCID 772306645-Formyl-5,6,7,8-tetrahydronaphthalene-1-carbonitrile

Procedure

5-Formyl-5,6,7,8-tetrahydronaphthalene-1-carbonitrile was prepared from 5-oxo-5,6,7,8-tetrahydronaphthalene-1-carbonitrile in an analogous fashion to that described above for the synthesis of 1-formyl-2,3-dihydro-1H-indene-4-carbonitrile (Steps B and C).

Sources & evidence

ORD record
ord-dd43553840264cada7883d8003264322
Source dataset
uspto-grants-2015_06
Patent number
US09056859B2

Reaction notes

Loading…