HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3-fluoro-4-nitrophenyl)acetic acid → 4-Amino-3-fluorophenylacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3-fluoro-4-nitrophenyl)acetic acid | HCID 2774665 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 4-Amino-3-fluorophenylacetic acid | HCID 2778324 | — |
Reaction Steps
To a solution of (3-fluoro-4-nitrophenyl)acetic acid (1 g, 5 mmol) in 30 mL of EtOAc was added 180 mg of Pd/C was stirred at room temperature under H2 atmosphere overnight. The reaction mixture was filtrated and concentrated to give (4-amino-3-fluorophenyl)acetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09056859B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-cc367f5c70864bcca07db82522367cec |
| Source note | uspto-grants-2015_06 |