HCID 18794322, compound → HCID 67518240, compound

HRID 2173409Notes

Reaction equation

HRID 2173409 reaction equation
CC1C=[C:6]([N:8]2C=N[N:10]=[N:9]2)C=CC=1CC(O)=O.[NH2:17][C:18]1[CH:23]=[CH:22][C:21]([CH2:24][C:25]([OH:27])=[O:26])=[C:20]([C:28]([F:31])([F:30])[F:29])[CH:19]=1>>[N:17]1([C:18]2[CH:23]=[CH:22][C:21]([CH2:24][C:25]([OH:27])=[O:26])=[C:20]([C:28]([F:29])([F:30])[F:31])[CH:19]=2)[CH:6]=[N:8][N:9]=[N:10]1

Participants

3

Reactant 2

HCID 18794322HCID 18794322, compoundHCID 67517423HCID 67517423, compound

Product 1

HCID 67518240HCID 67518240, compound

Procedure

[4-(1H-tetrazol-1-yl)-2-(trifluoromethyl)phenyl]acetic acid was prepared in a similar fashion to that described for the synthesis of [2-methyl-4-(1H-tetrazol-1-yl)phenyl]acetic acid starting from [4-amino-2-(trifluoromethyl)phenyl]acetic acid. LC-MS (IE, m/z): 273 [M+1]+.

Sources & evidence

ORD record
ord-2462fe7d251a4776bbbf65cab26f9145
Source dataset
uspto-grants-2015_06
Patent number
US09056859B2

Reaction notes

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