1-(Bromomethyl)-2-chloro-3-(trifluoromethyl)benzene → 5-tert-Butyl-3-(2-chloro-3-trifluoromethyl-benzyl)-7-(3,3-difluoro-pyrrolidin-1-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine

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In analogy to the procedure described for the synthesis of 5-tert-butyl-7-(3,3-difluoropyrrolidin-1-yl)-3-ethyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine (example 61), the title compound was prepared from 5-tert-butyl-7-(3,3-difluoropyrrolidin-1-yl)-3H-[1,2,3]triazolo [4,5-d]pyrimidine and 1-(bromomethyl)-2-chloro-3-(trifluoromethyl)benzene and isolated as light-yellow solid. MS(nm/e): 475.2 (MH+).

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