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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2173649Generated: November 3, 2026

5-tert-Butyl-3-(2-chloro-benzyl)-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidine → HCID 86683376, compound

https://huagongshe.com/reaction/2173649

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-tert-Butyl-3-(2-chloro-benzyl)-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidineHCID 1433953—
Reactant(S)-(+)-2-(Aminomethyl)pyrrolidineHCID 2734054—
Reactant5-tert-butyl-7-chloro-3-(2-chlorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidineHCID 86683284—
ProductHCID 86683376HCID 86683376—

Reaction Steps

In analogy to the procedure described for the synthesis of 5-tert-butyl-3-(2-chlorobenzyl)-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidine (example 1, step c), the title compound was prepared from 5-tert-butyl-7-chloro-3-(2-chlorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine and (S)-pyrrolidin-2-ylmethanamine. MS(m/e): 400.4 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09056866B2
Source datasetuspto-grants-2015_06
ORD IDord-c72ccc1b660b4a21aab04b2fabc83acb
Source noteuspto-grants-2015_06