HCID 86703344, compound → HCID 86703346, compound

HRID 2173674Notes

Reaction equation

HRID 2173674 reaction equation
OC1C=CC2CCCCN(CC)C=2C=1.C[O:16][C:17]1[CH:26]=[CH:25][C:24]2[CH2:27][CH2:28][CH2:29][CH2:30][N:22]3[C:23]=2[C:18]=1[CH2:19][CH2:20][CH2:21]3>>[OH:16][C:17]1[CH:26]=[CH:25][C:24]2[CH2:27][CH2:28][CH2:29][CH2:30][N:22]3[C:23]=2[C:18]=1[CH2:19][CH2:20][CH2:21]3

Participants

3

Reactant 2

HCID 86703344HCID 86703344, compoundHCID 86703345HCID 86703345, compound

Product 1

HCID 86703346HCID 86703346, compound

Procedure

The title compound was synthesized in a similar manner as 8-hydroxy-2,3,4,5-tetrahydro-1-ethylbenzo[b]azepine from 11-methoxy-2,3,5,6,7,8-hexahydro-1H-azepino[3,2,1-ij]quinoline: 1H NMR (DMSO-d6) δ 8.82 (s, 1H), 6.64 (d, 1H); 6.22 (d, 1H), 3.03-2.99 (m, 2H), 2.87-2.83 (m, 2H), 2.55-2.50 (m, 2H), 2.53-2.49 (m, 2H), 1.68-1.61 (m, 4H), 1.45-1.37 (m, 2H); MS expected 204 (C13H18NO, M+1), found 204.

Sources & evidence

ORD record
ord-ff6a5af284a14d4ca86d617aa02a6b05
Source dataset
uspto-grants-2015_06
Patent number
US09056885B2

Reaction notes

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