HCID 12466797, compound → HCID 86703347, compound

HRID 2173675Notes

Reaction equation

HRID 2173675 reaction equation
COC1C=CC2CCCCNC=2C=1.[CH3:14][O:15][C:16]1[CH:17]=[CH:18][C:19]2[C:25]([CH3:26])=[CH:24][CH2:23][C:22](=O)[NH:21][C:20]=2[CH:28]=1>>[CH3:14][O:15][C:16]1[CH:17]=[CH:18][C:19]2[C:25]([CH3:26])=[CH:24][CH2:23][CH2:22][NH:21][C:20]=2[CH:28]=1

Participants

3

Reactant 2

HCID 12466797HCID 12466797, compoundHCID 16244477HCID 16244477, compound

Product 1

HCID 86703347HCID 86703347, compound

Procedure

The title compound was synthesized following the procedure for synthesizing 8-methoxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine using 8-methoxy-5-methyl-1H-benzo[b]azepin-2(3H)-one (Aust. J. Chem. 1978, 31, 2031-2037) as starting material: 1H NMR (DMSO-d6) δ 7.28 (d, 1H), 6.46 (dd, 1H); 6.28 (d, 1H), 5.89 (t, 1H), 5.30 (s, 1H), 3.77 (s, 3H), 3.40 (t, 2H), 2.41 (q, 2H), 2.14 (d, 3H); MS expected 190 (C12H16NO, M+1), found 190.

Sources & evidence

ORD record
ord-fb97db2213c24830800e103878a55073
Source dataset
uspto-grants-2015_06
Patent number
US09056885B2

Reaction notes

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