5-Methoxynaphthalen-2-amine → HCID 86703354, compound

HRID 2173681Notes

Reaction equation

HRID 2173681 reaction equation
O[C:2]1[CH:11]=[CH:10][C:9]2[CH2:12][CH2:13][CH2:14]C[N:7]3[C:8]=2[C:3]=1[C:4](=[O:16])[CH2:5][CH2:6]3.C[O:18][C:19]1C=CC=C2[C:20]=1[CH:21]=[CH:22]C(N)=C2>>[OH:18][C:19]1[C:11]2[C:2](=[C:3]3[C:8]4=[C:9]([CH2:12][CH2:13][CH2:14][N:7]4[CH2:6][CH2:5][C:4]3=[O:16])[CH:10]=2)[CH:22]=[CH:21][CH:20]=1

Participants

3

Reactant 2

HCID 129927625-Methoxynaphthalen-2-amineHCID 86703351HCID 86703351, compound

Product 1

HCID 86703354HCID 86703354, compound

Procedure

The title compound was synthesized in a similar manner as 11-hydroxy-2,3,5,6,7,8-hexahydro-1H-azepino[3,2,1-ij]quinolone starting from 5-methoxy-2-aminonaphthalene: 1H NMR (DMSO-d6) δ 9.55 (s, 1H), 7.55 (s, 1H); 7.08-7.00 (m, 2H), 6.48 (dd, 1H), 3.14 (q, 4H), 2.86 (q, 2H), 2.02-1.86 (m, 4H); MS expected 240 (C16H18NO, M+1), found 240.

Sources & evidence

ORD record
ord-ca1873f2cc3a48f3a45ef490e3daacb2
Source dataset
uspto-grants-2015_06
Patent number
US09056885B2

Reaction notes

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