HCID 178499187, compound → HCID 178508423, compound

HRID 2173709Notes

Reaction equation

HRID 2173709 reaction equation
FC(F)(F)C1C=C(N[C:9]([C:11]2[C:16]([NH2:17])=[N:15][C:14]([C:18]([F:21])([F:20])[F:19])=[C:13]([Br:22])[N:12]=2)=[O:10])NN=1.C[O:26][C:27]([C:29]1[N:33]=[C:32]([NH2:34])[NH:31][N:30]=1)=[O:28]>>[NH2:17][C:16]1[C:11]([C:9]([NH:34][C:32]2[NH:31][N:30]=[C:29]([C:27]([OH:26])=[O:28])[N:33]=2)=[O:10])=[N:12][C:13]([Br:22])=[C:14]([C:18]([F:19])([F:21])[F:20])[N:15]=1

Participants

3

Reactant 2

HCID 178499187HCID 178499187, compoundHCID 178508420HCID 178508420, compound

Product 1

HCID 178508423HCID 178508423, compound

Procedure

The title compound was prepared analogously to 3-amino-6-bromo-5-trifluoromethyl-pyrazine-2-carboxylic acid (5-trifluoromethyl-2H-pyrazol-3-yl)-amide (Example 1) by replacing 3-(trifluoromethyl)-1H-pyrazol-5-amine with 5-amino-1H-[1,2,4]triazole-3-carboxylic acid methyl ester.

Sources & evidence

ORD record
ord-05da625be9ca4e55a42e0a64ba46cb14
Source dataset
uspto-grants-2015_06
Patent number
US09056867B2

Reaction notes

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