HCID 86701488, compound → HCID 178489066, compound

Participants

Reaction Steps

(±)-tert-Butyl 4-(1-(5-cyano-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-benzo[d]imidazol-2-yl)-1-hydroxyethyl)-5-methoxy-7-methyl-1H-indole-1-carboxylate and (±)-tert-butyl 4-(1-(6-cyano-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-benzo[d]imidazol-2-yl)-1-hydroxyethyl)-5-methoxy-7-methyl-1H-indole-1-carboxylate was converted in the title compound using the same procedure described in Example 24-B. 1H NMR (400 MHz, DMSO-d6) δ ppm 12.30 (s, 1H) 10.86 (br. s., 1H) 8.10 (s) 7.63-7.84 (m) 7.38-7.55 (m, 2H) 7.21 (q, J=3.12 Hz, 1H) 6.47-6.77 (m, 1H) 6.00 (d, J=1.01 Hz, 1H) 3.26-3.30 (m, 3H) 2.40-2.45 (m, 3H) 2.03 (s, 3H). HRMS calcd. for C20H18N4O2 (M+H)+ 347.1508. found 347.1510.

Provenance & Evidence