HCID 86701497, compound → HCID 178429087, compound

Participants

Reaction Steps

The title compound was synthesized from a mixture of (±)-tert-butyl 5-(2-amino-2-oxoethoxy)-4-(1-(5-cyano-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-benzo[d]imidazol-2-yl)-1-hydroxyethyl)-7-methyl-1H-indole-1-carboxylate and (±)-tert-butyl 5-(2-amino-2-oxoethoxy)-4-(1-(6-cyano-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-benzo[d]imidazol-2-yl)-1-hydroxyethyl)-7-methyl-1H-indole-1-carboxylate as described in Example 24-B. 1H NMR (TFA salt, 400 MHz, MeOH-d4) δ ppm 8.04 (s, 1H) 7.63-7.85 (m, 2H) 7.31 (d, J=3.28 Hz, 1H) 7.01 (d, J=3.28 Hz, 1H) 6.69 (s, 1H) 4.37-4.49 (m, 1H) 4.24-4.35 (m, 1H) 2.49 (s, 3H) 2.31 (s, 3H). HRMS calcd. for C21H19N5O3 (M+H)+ 390.1561. found 390.1561.

Provenance & Evidence