HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium cyclopropyltrifluoroborate → 5-Cyclopropyl-7-methyl-1-tosyl-1H-indole-4-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium cyclopropyltrifluoroborate | HCID 23697338 | — |
| Reactant | 5-chloro-7-methyl-4-(((tetrahydro-2H-pyran-2-yl)oxy)methyl)-1-tosyl-1H-indole | HCID 86701538 | — |
| Product | 5-Cyclopropyl-7-methyl-1-tosyl-1H-indole-4-carbaldehyde | HCID 72191828 | — |
Reaction Steps
The title compound was synthesized starting from 5-chloro-7-methyl-4-(((tetrahydro-2H-pyran-2-yl)oxy)methyl)-1-tosyl-1H-indole as described in Example 48-A to 48-C using potassium cyclopropyltrifluoroborate in place of potassium ethylrifluoroborate in Example 48-A. MS (ESI+) m/z 354.2 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09056874B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-8a47e95cc66a47f6aca14675a012506d |
| Source note | uspto-grants-2015_06 |