Sulfuric Acid → HCID 86701551, compound

HRID 2173984Notes

Reaction equation

HRID 2173984 reaction equation
[C:1]([C:3]1[C:4]([CH3:16])=[C:5]([NH:12]C(=O)C)[C:6]([N+:9]([O-:11])=[O:10])=[CH:7][CH:8]=1)#[N:2].OS(O)(=O)=O>O>[NH2:12][C:5]1[C:4]([CH3:16])=[C:3]([CH:8]=[CH:7][C:6]=1[N+:9]([O-:11])=[O:10])[C:1]#[N:2]

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 86701550HCID 86701550, compound

Product 1

HCID 86701551HCID 86701551, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
100 °C

Procedure

N-(3-cyano-2-methyl-6-nitrophenyl)acetamide (0.37 g, 1.7 mmol) was added to a 2N aq. H2SO4 solution (10 mL). The reaction was heated to 100° C. for 6 hr. The reaction mixture was cooled to rt and poured into iced water. The solid precipitate was collected by filtration, and then washed with water several times to give the title compound. MS (ESI−) m/z 176.1 (M−H).

Workup

  1. temperatureThe reaction mixture was cooled to rt
  2. filtrationThe solid precipitate was collected by filtration
  3. washwashed with water several times

Sources & evidence

ORD record
ord-1ed02bbb0c6a44328b4b191c62dccc7a
Source dataset
uspto-grants-2015_06
Patent number
US09056874B2

Reaction notes

Loading…