HCID 86701611, compound → HCID 178424038, compound

HRID 2174016Notes

Reaction equation

[CH3:1][C:2]1[CH:10]=[C:9]([CH3:11])[C:8]2[N:7](S(C3C=CC(C)=CC=3)(=O)=O)[CH:6]=[CH:5][C:4]=2[C:3]=1[C:22]([C:24]1[N:28](COCC[Si](C)(C)C)[C:27]2[CH:37]=[CH:38][C:39]([C:41]#[N:42])=[CH:40][C:26]=2[N:25]=1)=[O:23].CC1C=C(C)C2N(S(C3C=CC(C)=CC=3)(=O)=O)C=CC=2C=1C(C1N(COCC[Si](C)(C)C)C2C=C(C#N)C=CC=2N=1)=O>>[CH3:1][C:2]1[CH:10]=[C:9]([CH3:11])[C:8]2[NH:7][CH:6]=[CH:5][C:4]=2[C:3]=1[C:22]([C:24]1[NH:28][C:27]2[CH:37]=[CH:38][C:39]([C:41]#[N:42])=[CH:40][C:26]=2[N:25]=1)=[O:23]

Participants

Reactant 2

HCID 86701611HCID 86701611, compound

HCID 86701612HCID 86701612, compound

Product 1

HCID 178424038HCID 178424038, compound

Procedure

The title compound was synthesized from a mixture of 2-(5,7-dimethyl-1-tosyl-1H-indole-4-carbonyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-benzo[d]imidazole-5-carbonitrile and 2-(5,7-dimethyl-1-tosyl-1H-indole-4-carbonyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-benzo[d]imidazole-6-carbonitrile (Example 75-A) analogously to Example 64-B and 64-C. MS (ESI+) m/z 315.1 (M+H).

Sources & evidence

ORD record: ord-722e64ef3b5b41c9ab22a553025cc680
Source dataset: uspto-grants-2015_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09056874B2

Reaction notes

Loading…