HCID 86701488, compound → HCID 178437483, compound

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The title compound was synthesized from a mixture of (±)-tert-butyl 4-(1-(5-cyano-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-benzo[d]imidazol-2-yl)-1-hydroxyethyl)-5-methoxy-7-methyl-1H-indole-1-carboxylate and (±)-tert-butyl 4-(1-(6-cyano-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-benzo[d]imidazol-2-yl)-1-hydroxy ethyl)-5-methoxy-7-methyl-1H-indole-1-carboxylate (Example 26-A) in a similar manner as shown in Example 114. 1H NMR (400 MHz, DMSO-d6) δ ppm 8.07 (s) 7.65-7.84 (m) 7.44-7.56 (m) 7.15-7.36 (m, 1H) 6.82 (d, J=2.91 Hz, 1H) 6.58 (dd, J=14.84, 1.71 Hz, 1H) 6.14 (dd, J=2.97, 1.96 Hz, 1H) 5.56-5.75 (m, 1H) 3.57 (d, J=0.88 Hz, 3H) 2.53 (br. s., 3H). HRMS calcd. for C20H16N4O (M+H)+ 329.1402. found 329.1395.

Provenance & Evidence