HCID 86686938, compound → HCID 18533175, compound

Participants

Reaction Steps

16.5 g said 4′-chloro-4(trichloromethyl sulfenyl)benzophenone is added in a 100 ml three-neck flask, and then 30 g methanol is added. Under nitrogen protection, the solution is heated with stirring to reflux. After reacting for 3 hours, it is analyzed to find that 4′-chloro-4(trichloromethyl sulfenyl)benzophenone is completely consumed. Distilling to remove the methanol and all low-boiling-point substances, the residue has a mass of 11.0 g, and the yield is 98%. Said residue is recrystallized in a mixed solvent consisting of dichloroethane and petroleum ether in a weight ratio 1:3 to obtain 9.5 g white flake crystal with a purity of 99.0%, and the melting point is 157-161° C. 1H-NMR data (solvent CDCl3): δ3.656 ppm, s, 1H, δ7.320, 7.348 ppm, d, 2H, δ7.443, 7.471 ppm, d, 2H; δ7.644, 7.672 ppm, d, 2H, δ7.698, 7.726 ppm, d, 2H.

Provenance & Evidence