反应详情

To a solution of sodium caffeate (210; 7.35 mmol) in DMSO (20 mL) at 60°-70° C. was added glycidyl cinnamate (130; 7.35 mmol). The resulting mixture was heated to 60°-75° C. with continuous stirring for 22-24 h and then distilled under reduced pressure to yield compound (Ie). 1H-NMR (CD3OD) δ 4.16 (s, 1H), 2.28 (s, 4H), 6.29 (d, 1H, J=16 Hz), 6.65 (d, 1H, J=16 Hz), 6.75 (d, 1H, J=8 Hz), 6.93 (1H, dd, J=8, 2 Hz), 7.03 (d, 1H, J=2 Hz), 7.37 (m, 1H), 7.38 (m, 1H), 7.55 (m), 7.59 (d, 1H, J=16 Hz), 7.72 (d, 1H, J=16 Hz).

1. temperatureThe resulting mixture was heated to 60°-75° C.
2. distillationdistilled under reduced pressure
3. customto yield compound (Ie)