HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Malonate → Diethyl 2-vinylcyclopropane-1,1-dicarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Malonate | HCID 7761 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | trans-1,4-Dibromo-2-butene | HCID 641245 | — |
| Reactant | Tricaprylylmethyl ammonium chloride | HCID 77620884 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Diethyl 2-vinylcyclopropane-1,1-dicarboxylate | HCID 111025 | 89% |
Reaction Steps
Patent Document 1 and Example 21 of Patent Document 2 describe that trans-1,4-dibromo-2-butene is allowed to react with diethyl malonate in dichloromethane in the presence of potassium hydroxide (90% flake form) and tricaprylylmethylammonium chloride, so as to obtain 1,1-di-ethoxycarbonyl-2-vinylcyclopropane at a yield of 89%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09061991B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-29b86c7a8ab84cbfaaab475bfc5752d2 |
| Source note | uspto-grants-2015_06 |