O-ethylhydroxylamine hydrochloride → HCID 86707232, compound

HRID 2174672Notes

Reaction equation

HRID 2174672 reaction equation
[N:1]1[N:2]([C:10]2[N:31]=[CH:30][CH:29]=[CH:28][C:11]=2[C:12]([NH:14][CH:15]([CH2:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH:16]([OH:20])[C:17](O)=[O:18])=[O:13])[CH:3]=[C:4]2[C:9]=1[CH:8]=[CH:7][CH:6]=[CH:5]2.Cl.[CH2:33]([O:35][NH2:36])[CH3:34]>>[CH2:33]([O:35][NH:36][C:17](=[O:18])[CH:16]([OH:20])[CH:15]([NH:14][C:12](=[O:13])[C:11]1[CH:28]=[CH:29][CH:30]=[N:31][C:10]=1[N:2]1[CH:3]=[C:4]2[C:9]([CH:8]=[CH:7][CH:6]=[CH:5]2)=[N:1]1)[CH2:21][C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1)[CH3:34]

Participants

3

Reactant 2

HCID 76850O-ethylhydroxylamine hydrochlorideHCID 67958233HCID 67958233, compound

Product 1

HCID 86707232HCID 86707232, compound

Procedure

The reaction was carried out in analogy to reaction step 3.1 by reacting 3-[2-(2H-indazol-2-yl)nicotinamido]-2-hydroxy-4-phenylbutanoic acid and O-ethylhydroxylamine hydrochloride.

Workup

  1. customThe reaction was carried out in analogy to reaction step 3.1

Sources & evidence

ORD record
ord-b802550947f345fabd29f87dc438d9bc
Source dataset
uspto-grants-2015_06
Patent number
US09062027B2

Reaction notes

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