HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Iodo-3-methylbenzoic acid → Methyl 2-iodo-3-methylbenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Iodo-3-methylbenzoic acid | HCID 2759365 | — |
| Reactant | Dichloromethane methanol | HCID 21226129 | — |
| Product | Methyl 2-iodo-3-methylbenzoate | HCID 13924925 | — |
Reaction Steps
2-iodo-3-methylbenzoic acid (595 mg, 2.27 mmol) was dissolved in DCM/MeOH=1/1 (5 ml) at 0° C., then TMS-CH2N2 (2M in Et2O, 1.4 ml, 2.8 mmol) was added. After 1.5 hours at RT solvents were evaporated. Yield 630 mg yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09062033B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-8262197c8ae54385a67703552e0e64e3 |
| Source note | uspto-grants-2015_06 |