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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2175015Generated: October 29, 2026

5-Fluoro-2-iodobenzoic acid → 2-Fluoro-6-(2H-1,2,3-triazol-2-yl)benzoic acid

https://huagongshe.com/reaction/2175015

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Fluoro-2-iodobenzoic acidHCID 13158583—
Reactant5-fluoro-2-(2H-1,2,3-triazol-2-yl)benzoic acidHCID 67086948—
Product2-Fluoro-6-(2H-1,2,3-triazol-2-yl)benzoic acidHCID 67086627—

Reaction Steps

The title compound was prepared in a manner analogous to Intermediate 41, substituting 6-fluoro-2-iodo-benzoic acid for 5-fluoro-2-iodo-benzoic acid. 1H NMR (400 MHz, CD3OD): 7.96 (s, 2H), 7.87-7.82 (m, 1H), 7.70 (td, J=8.1, 5.1 Hz, 1H), 7.59 (ddd, J=9.7, 8.4, 1.4 Hz, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09062044B2
Source datasetuspto-grants-2015_06
ORD IDord-82d9da1a4b9041cb8df8c8d8db410c4e
Source noteuspto-grants-2015_06