2-Chloro-4,6-dimethylpyrimidine → HCID 52915316, compound

Participants

Reaction Steps

The title compound was prepared in a manner analogous to Example 1, substituting (1R,6S) biphenyl-2-yl-(3,8-diaza-bicyclo[4.2.0]oct-8-yl)-methanone for biphenyl-2-yl-(3,8-diaza-bicyclo[4.2.0]oct-8-yl)-methanone and 2-chloro-4,6-dimethyl-pyrimidine for 2-chloro quinoxaline. MS (ESI) mass calcd. for C25H26N4O, 398.50; m/z found 399.2 [M+H]+. 1H NMR (CDCl3): 7.54-7.31 (m, 7H), 7.25-7.11 (m, 2H), 6.33-6.23 (m 1H), 4.64-4.36 (0.5H), 4.00-3.39 (m, 5H), 3.25-2.85 (m, 1.25H), 2.60-2.37 (m, 1.25H), 2.33 (s, 3H), 2.25 (s, 3H), 2.00-1.37 (m, 2H).

Provenance & Evidence